Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 19 Researches
7.5
USERS' SCORE
Moderately Good
Based on 18 Reviews
7.8
Supplement Facts
Serving Size: 1 Tablet
Serving Per Container: 275
Amount Per Serving
%DV
Total Carbohydrates
1 g
<1%**
Calcium (as Calcium Carbonate)
98 mg
8%
Proprietary BlendCascara Sagrada powder (bark), Fennel powder (seed), Psyllium powder (seed husk), Ginger powder (rhizome), Acacia Gum, Barley Grass powder (aerial), Beet powder (root), Glucomannan, Karaya Gum, Lemon Peel powder (peel), Oat Bran powder, Peppermint powder (leaf), Red Raspberry (Rubus idaeus) powder (leaf), Slippery Elm powder (bark), Chlorella powder, Guar Gum, Lactobacillus acidophilus (1 million/g *** )
542 mg
†
Top Medical Research Studies
9
Lactobacillus drink benefits IBS-C
We explored the impact of a Lactobacillus-containing cultured milk drink on individuals with constipation-predominant irritable bowel syndrome (IBS-C). Over 30 days, participants consumed this drink daily while we assessed their clinical symptoms and inflammatory markers.
Impressively, 97.4% reported improvement in symptoms, along with noticeable reductions in intestinal transit time and fecal pH. Evidence also showed lowered levels of pro-inflammatory cytokines in IBS-C participants, supporting potential adjunctive benefits of this treatment for IBS-C patients.
Impressively, 97.4% reported improvement in symptoms, along with noticeable reductions in intestinal transit time and fecal pH. Evidence also showed lowered levels of pro-inflammatory cytokines in IBS-C participants, supporting potential adjunctive benefits of this treatment for IBS-C patients.
Read More
9
This study looked into the effects of two probiotic strains, DDS-1 and UABla-12, on alleviating abdominal pain and other IBS symptoms.
We observed that participants taking these probiotics experienced notable reductions in pain severity and overall symptom scores compared to those receiving a placebo.
Specifically, both probiotic groups reported improved bowel habits and stool consistency, enhancing quality of life for adults facing IBS.
Overall, the results suggest that these probiotic strains can be beneficial for managing symptoms of irritable bowel syndrome.
We observed that participants taking these probiotics experienced notable reductions in pain severity and overall symptom scores compared to those receiving a placebo.
Specifically, both probiotic groups reported improved bowel habits and stool consistency, enhancing quality of life for adults facing IBS.
Overall, the results suggest that these probiotic strains can be beneficial for managing symptoms of irritable bowel syndrome.
Read More
8
Probiotics show promise for IBS relief
We evaluated the efficacy of quadruple-coated probiotics in patients with irritable bowel syndrome (IBS). One hundred and nine participants were randomly assigned to either the probiotic or placebo group for four weeks.
Participants recorded their symptoms, and we noted a significant improvement in overall IBS symptoms, particularly in female and constipation-predominant patients. The results were promising, suggesting that these probiotics can provide relief. However, further studies are needed to explore why women respond differently to this treatment.
Participants recorded their symptoms, and we noted a significant improvement in overall IBS symptoms, particularly in female and constipation-predominant patients. The results were promising, suggesting that these probiotics can provide relief. However, further studies are needed to explore why women respond differently to this treatment.
Read More
Most Useful Reviews
9
Effective for constipation
9 people found this helpful
The intestines have responded to two pills, but hydration is crucial. I suffered from severe constipation, going three days without a bowel movement despite normal tests. My intestines were weak, so I tried this product. The manufacturer claimed I could achieve 2-3 bowel movements daily. I began with one tablet morning and evening, and the effect was noticeable after two daily tablets. I found relief and plan to increase my dose slightly at night. It is essential to drink plenty of water with the pill and throughout the day – at least eight glasses. Initially, I neglected my water intake and felt unwell, but after hydrating properly, everything normalised. The effect is remarkable; I'm truly satisfied with the results. The tablets are small, green, and easy to swallow. I wholeheartedly recommend them.
Read More
9
Highly recommended supplement
1 people found this helpful
I tried this for the first time and it works wonderfully. The composition is impressive, and it has a pleasant licorice smell. I take one in the morning and one at night, and I highly recommend this supplement.
Read More
9
Restores gut health
1 people found this helpful
After using many bottles, the stress surrounding my bowel movements is gone. Other detox supplements I tried didn't work. Once this ColonCleanse arrived, my intestinal condition improved. Individual differences exist, but I plan to keep using it.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 19 Researches
7.5
- All Researches
9.5
This randomized, single-blinded trial evaluated the impact of probiotics, specifically Lactobacillus acidophilus and plantarum, on patients with diarrhea-predominant irritable bowel syndrome (IBS-D).
We found that when added to standard IBS treatment, these probiotics significantly improved symptoms over a 12-week period.
Group B, the probiotic group, experienced better results, including fewer days with pain and greater satisfaction with bowel habits. While both groups saw reductions in IBS severity, the probiotics led to complete remission in many patients, which is promising for future treatment guidelines.
We found that when added to standard IBS treatment, these probiotics significantly improved symptoms over a 12-week period.
Group B, the probiotic group, experienced better results, including fewer days with pain and greater satisfaction with bowel habits. While both groups saw reductions in IBS severity, the probiotics led to complete remission in many patients, which is promising for future treatment guidelines.
Read More
9.5
This randomized, single-blinded trial evaluated the impact of probiotics, specifically Lactobacillus acidophilus and plantarum, on patients with diarrhea-predominant irritable bowel syndrome (IBS-D).
We found that when added to standard IBS treatment, these probiotics significantly improved symptoms over a 12-week period.
Group B, the probiotic group, experienced better results, including fewer days with pain and greater satisfaction with bowel habits. While both groups saw reductions in IBS severity, the probiotics led to complete remission in many patients, which is promising for future treatment guidelines.
We found that when added to standard IBS treatment, these probiotics significantly improved symptoms over a 12-week period.
Group B, the probiotic group, experienced better results, including fewer days with pain and greater satisfaction with bowel habits. While both groups saw reductions in IBS severity, the probiotics led to complete remission in many patients, which is promising for future treatment guidelines.
Read More
9
Lactobacillus drink benefits IBS-C
We explored the impact of a Lactobacillus-containing cultured milk drink on individuals with constipation-predominant irritable bowel syndrome (IBS-C). Over 30 days, participants consumed this drink daily while we assessed their clinical symptoms and inflammatory markers.
Impressively, 97.4% reported improvement in symptoms, along with noticeable reductions in intestinal transit time and fecal pH. Evidence also showed lowered levels of pro-inflammatory cytokines in IBS-C participants, supporting potential adjunctive benefits of this treatment for IBS-C patients.
Impressively, 97.4% reported improvement in symptoms, along with noticeable reductions in intestinal transit time and fecal pH. Evidence also showed lowered levels of pro-inflammatory cytokines in IBS-C participants, supporting potential adjunctive benefits of this treatment for IBS-C patients.
Read More
9
This study looked into the effects of two probiotic strains, DDS-1 and UABla-12, on alleviating abdominal pain and other IBS symptoms.
We observed that participants taking these probiotics experienced notable reductions in pain severity and overall symptom scores compared to those receiving a placebo.
Specifically, both probiotic groups reported improved bowel habits and stool consistency, enhancing quality of life for adults facing IBS.
Overall, the results suggest that these probiotic strains can be beneficial for managing symptoms of irritable bowel syndrome.
We observed that participants taking these probiotics experienced notable reductions in pain severity and overall symptom scores compared to those receiving a placebo.
Specifically, both probiotic groups reported improved bowel habits and stool consistency, enhancing quality of life for adults facing IBS.
Overall, the results suggest that these probiotic strains can be beneficial for managing symptoms of irritable bowel syndrome.
Read More
8
Lactobacillus aids IBS-related depression
We examined how consuming a cultured milk drink with Lactobacillus acidophilus might impact depression in patients with irritable bowel syndrome (IBS). The study involved 110 participants who were divided into groups to receive either the probiotic drink or a placebo over 12 weeks.
Those with subthreshold depression experienced significant reductions in depression scores. The probiotic group even saw boosts in serotonin levels and improvements in quality of life. Although everyone reported reduced IBS severity, the probiotics specifically showed notable potential in managing depressive symptoms linked to IBS.
Those with subthreshold depression experienced significant reductions in depression scores. The probiotic group even saw boosts in serotonin levels and improvements in quality of life. Although everyone reported reduced IBS severity, the probiotics specifically showed notable potential in managing depressive symptoms linked to IBS.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 18 Reviews
7.8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective for constipation
9 people found this helpful
The intestines have responded to two pills, but hydration is crucial. I suffered from severe constipation, going three days without a bowel movement despite normal tests. My intestines were weak, so I tried this product. The manufacturer claimed I could achieve 2-3 bowel movements daily. I began with one tablet morning and evening, and the effect was noticeable after two daily tablets. I found relief and plan to increase my dose slightly at night. It is essential to drink plenty of water with the pill and throughout the day – at least eight glasses. Initially, I neglected my water intake and felt unwell, but after hydrating properly, everything normalised. The effect is remarkable; I'm truly satisfied with the results. The tablets are small, green, and easy to swallow. I wholeheartedly recommend them.
Read More
9
Highly recommended supplement
1 people found this helpful
I tried this for the first time and it works wonderfully. The composition is impressive, and it has a pleasant licorice smell. I take one in the morning and one at night, and I highly recommend this supplement.
Read More
9
Restores gut health
1 people found this helpful
After using many bottles, the stress surrounding my bowel movements is gone. Other detox supplements I tried didn't work. Once this ColonCleanse arrived, my intestinal condition improved. Individual differences exist, but I plan to keep using it.
Read More
9
Smooth operation
This product works smoothly without causing any stomach pain. I've achieved regular bowel movements, and honestly, what more could I ask for?
Read More
7.5
Awesome bowel benefits
This product is of excellent quality! I take it before meals along with Inulin, three pills roughly an hour prior. The benefits for bowel movement, intestinal transit, and constipation are remarkable. The pills are tasteless and easy to swallow, and I strongly recommend it!
Read More
Frequently Asked Questions
9
Effective for constipation
9 people found this helpful
The intestines have responded to two pills, but hydration is crucial. I suffered from severe constipation, going three days without a bowel movement despite normal tests. My intestines were weak, so I tried this product. The manufacturer claimed I could achieve 2-3 bowel movements daily. I began with one tablet morning and evening, and the effect was noticeable after two daily tablets. I found relief and plan to increase my dose slightly at night. It is essential to drink plenty of water with the pill and throughout the day – at least eight glasses. Initially, I neglected my water intake and felt unwell, but after hydrating properly, everything normalised. The effect is remarkable; I'm truly satisfied with the results. The tablets are small, green, and easy to swallow. I wholeheartedly recommend them.
7.5
Temporary solution
1 people found this helpful
This product helps improve bowel function swiftly. However, once I stop using it, my issues return, despite maintaining a proper diet and taking additional fibre.
2
Not effective
I saw no improvement after taking these tablets for a month (one in the morning and one in the evening). I still experienced three-day intervals between bowel movements and needed to take them daily. It did not meet my expectations for a straightforward colon cleanse.
9
Smooth operation
This product works smoothly without causing any stomach pain. I've achieved regular bowel movements, and honestly, what more could I ask for?
9
Restores gut health
1 people found this helpful
After using many bottles, the stress surrounding my bowel movements is gone. Other detox supplements I tried didn't work. Once this ColonCleanse arrived, my intestinal condition improved. Individual differences exist, but I plan to keep using it.
7.5
Awesome bowel benefits
This product is of excellent quality! I take it before meals along with Inulin, three pills roughly an hour prior. The benefits for bowel movement, intestinal transit, and constipation are remarkable. The pills are tasteless and easy to swallow, and I strongly recommend it!
7.5
Gentle on the gut
2 people found this helpful
The product acts gently, causing no intestinal discomfort. With just two tablets daily, I maintain a normal bowel movement. I'm committed to taking it for a month and will update my review then.
9.5
This randomized, single-blinded trial evaluated the impact of probiotics, specifically Lactobacillus acidophilus and plantarum, on patients with diarrhea-predominant irritable bowel syndrome (IBS-D).
We found that when added to standard IBS treatment, these probiotics significantly improved symptoms over a 12-week period.
Group B, the probiotic group, experienced better results, including fewer days with pain and greater satisfaction with bowel habits. While both groups saw reductions in IBS severity, the probiotics led to complete remission in many patients, which is promising for future treatment guidelines.
We found that when added to standard IBS treatment, these probiotics significantly improved symptoms over a 12-week period.
Group B, the probiotic group, experienced better results, including fewer days with pain and greater satisfaction with bowel habits. While both groups saw reductions in IBS severity, the probiotics led to complete remission in many patients, which is promising for future treatment guidelines.
9
This study looked into the effects of two probiotic strains, DDS-1 and UABla-12, on alleviating abdominal pain and other IBS symptoms.
We observed that participants taking these probiotics experienced notable reductions in pain severity and overall symptom scores compared to those receiving a placebo.
Specifically, both probiotic groups reported improved bowel habits and stool consistency, enhancing quality of life for adults facing IBS.
Overall, the results suggest that these probiotic strains can be beneficial for managing symptoms of irritable bowel syndrome.
We observed that participants taking these probiotics experienced notable reductions in pain severity and overall symptom scores compared to those receiving a placebo.
Specifically, both probiotic groups reported improved bowel habits and stool consistency, enhancing quality of life for adults facing IBS.
Overall, the results suggest that these probiotic strains can be beneficial for managing symptoms of irritable bowel syndrome.
8
We investigated the impact of multispecies probiotics, including Lactobacillus acidophilus, in treating irritable bowel syndrome (IBS). In a randomized, double-blind study with 49 participants, those taking probiotics experienced significantly more symptom relief than those on a placebo after four weeks.
The probiotics not only eased abdominal discomfort and bloating but also positively altered gut bacteria. Our findings suggest that multispecies probiotics could be a valuable option for managing IBS symptoms.
The probiotics not only eased abdominal discomfort and bloating but also positively altered gut bacteria. Our findings suggest that multispecies probiotics could be a valuable option for managing IBS symptoms.
7
We examined how different gut bacteria in patients with diarrhea-predominant irritable bowel syndrome (IBS-D) responded to probiotic treatment. In our study, patients were split into a probiotic group and a placebo group, with fecal samples collected before and after eight weeks.
Although we found changes in fecal bacteria due to probiotics, the results indicated that not all patients benefited equally. We noted specific gut bacteria correlated with symptom relief, pointing to potential indicators for predicting who might not respond to probiotics.
Although we found changes in fecal bacteria due to probiotics, the results indicated that not all patients benefited equally. We noted specific gut bacteria correlated with symptom relief, pointing to potential indicators for predicting who might not respond to probiotics.
References
- Liu WQ, Shu L, Zhou X, Wang XF, Liu S, et al. Evaluation of the efficacy of polyethylene glycol in combination with different doses of linaclotide in a fractionated bowel preparation for colonoscopy: a prospective randomized controlled study. Int J Colorectal Dis. 2024;39:143. 10.1007/s00384-024-04718-4
- Tarasiuk A, Mosińska P, Fichna J. Triphala: current applications and new perspectives on the treatment of functional gastrointestinal disorders. Chin Med. 2018;13:39. 10.1186/s13020-018-0197-6
- Tooth D, Garsed K, Singh G, Marciani L, Lam C, et al. Characterisation of faecal protease activity in irritable bowel syndrome with diarrhoea: origin and effect of gut transit. Gut. 2014;63:753. 10.1136/gutjnl-2012-304042
- Sarkawi M, Raja Ali RA, Abdul Wahab N, Abdul Rathi ND, Mokhtar NM. A randomized, double-blinded, placebo-controlled clinical trial on Lactobacillus-containing cultured milk drink as adjuvant therapy for depression in irritable bowel syndrome. Sci Rep. 2024;14:9478. 10.1038/s41598-024-60029-2
- Shanshal SA, Alsaaty MH, Al-Qazaz H, Al-Zidan RN. Two Lactobacilli strains as adjuvant therapy in the management of irritable bowel syndrome: a randomized control trial. Ceska Slov Farm. 2024;72:233.
- Shanshal SA, Alsaaty MH, Al-Qazaz H, Al-Zidan RN. Two Lactobacilli strains as adjuvant therapy in the management of irritable bowel syndrome: a randomized control trial. Ceska Slov Farm. 2024;73:233.
- Chang YH, Choi YJ, Shin CM, Moon JS, Kim TY, et al. Efficacy of Quadruple-coated Probiotics in Patients With Irritable Bowel Syndrome: A Randomized, Double-blind, Placebo-controlled, Parallel-group Study. J Neurogastroenterol Motil. 2024;30:73. 10.5056/jnm23036
- Drozdov VN, Shikh EV, Astapovskii AA, Khalaidzheva KN, Solovieva SA, et al. [Clinical efficacy of a modern probiotic for the correction of intestinal microflora in patients with irritable bowel syndrome with diarrhea and antibiotic-associated diarrhea]. Vopr Pitan. 2023;92:92. 10.33029/0042-8833-2023-92-4-92-103
- Cocetta V, Giacomini I, Tinazzi M, Berretta M, Quagliariello V, et al. Maintenance of intestinal epithelial barrier integrity by a combination of probiotics, herbal extract, and vitamins. Minerva Pediatr (Torino). 2023. 10.23736/S2724-5276.23.07128-8
- Shin SY, Park S, Moon JM, Kim K, Kim JW, et al. Compositional Changes in the Gut Microbiota of Responders and Non-responders to Probiotic Treatment Among Patients With Diarrhea-predominant Irritable Bowel Syndrome: A Post Hoc Analysis of a Randomized Clinical Trial. J Neurogastroenterol Motil. 2022;28:642. 10.5056/jnm21202
- Mokhtar NM, Jaafar NM, Alfian E, Mohd Rathi ND, Abdul Rani R, et al. Clinical assessment and cytokines level in constipation-predominant irritable bowel syndrome participants treated with Lactobacillus-containing cultured milk drink. Acta Gastroenterol Belg. 2021;84:585. 10.51821/84.4.009
- Skrzydło-Radomańska B, Prozorow-Król B, Cichoż-Lach H, Majsiak E, Bierła JB, et al. The Effectiveness of Synbiotic Preparation Containing and Probiotic Strains and Short Chain Fructooligosaccharides in Patients with Diarrhea Predominant Irritable Bowel Syndrome-A Randomized Double-Blind, Placebo-Controlled Study. Nutrients. 2020;12. 10.3390/nu12071999
- Martoni CJ, Srivastava S, Leyer GJ. DDS-1 and UABla-12 Improve Abdominal Pain Severity and Symptomology in Irritable Bowel Syndrome: Randomized Controlled Trial. Nutrients. 2020;12. 10.3390/nu12020363
- Sadrin S, Sennoune S, Gout B, Marque S, Moreau J, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis. 2020;52:534. 10.1016/j.dld.2019.12.009
- Preston K, Krumian R, Hattner J, de Montigny D, Stewart M, et al. Lactobacillus acidophilus CL1285, Lactobacillus casei LBC80R and Lactobacillus rhamnosus CLR2 improve quality-of-life and IBS symptoms: a double-blind, randomised, placebo-controlled study. Benef Microbes. 2018;9:697. 10.3920/BM2017.0105
- Leventogiannis K, Gkolfakis P, Spithakis G, Tsatali A, Pistiki A, et al. Effect of a Preparation of Four Probiotics on Symptoms of Patients with Irritable Bowel Syndrome: Association with Intestinal Bacterial Overgrowth. Probiotics Antimicrob Proteins. 2019;11:627. 10.1007/s12602-018-9401-3
- Bogovič Matijašić B, Obermajer T, Lipoglavšek L, Sernel T, Locatelli I, et al. Effects of synbiotic fermented milk containing Lactobacillus acidophilus La-5 and Bifidobacterium animalis ssp. lactis BB-12 on the fecal microbiota of adults with irritable bowel syndrome: A randomized double-blind, placebo-controlled trial. J Dairy Sci. 2016;99:5008. 10.3168/jds.2015-10743
- Yoon H, Park YS, Lee DH, Seo JG, Shin CM, et al. Effect of administering a multi-species probiotic mixture on the changes in fecal microbiota and symptoms of irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial. J Clin Biochem Nutr. 2015;57:129. 10.3164/jcbn.15-14
- Yoon JS, Sohn W, Lee OY, Lee SP, Lee KN, et al. Effect of multispecies probiotics on irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial. J Gastroenterol Hepatol. 2014;29:52. 10.1111/jgh.12322
